COURSE OBJECTIVES

The course pharmaceutical analysis is designed to provide students with the ability to select and use appropriate methods for the qualitative and quantitative analysis of drugs. The course is mainly aimed to explain the fundamental analytical methods of drug analysis including the theoretical background and the calculations needed with their applications in pharmaceutical analysis. They will also learn the analysis of drugs by using latest techniques including theory and instrumentation of atomic absorption & emission spectroscopy, flame photometry, I.R., Mass, NMR, UV/Visible spectroscopy. It will also include the study of column, thin layer, gas-liquid chromatography, HPLC and GC-MS. Potentiometry, polarography, radiochemical techniques and differential scanning colorimetry.

COURSE LEARNING OUTCOMES (CLO)

CLO: 1. To understand the basic principles of different chromatographic and spectroscopic techniques.
CLO: 2. To apply the basic knowledge of chromatographic and spectroscopic techniques for structural elucidation
CLO: 3. 3 To analyze the spectrum and chromatogram of unknown chemical entities.

COURSE CONTENTS

  1. SPECTROSCOPIC METHODS:
    • Theory, Instrumentation and Pharmaceutical Applications of the following Spectroscopic Methods:
    • Atomic Absorption and Emission Spectroscopy
    • Molecular Fluorescence Spectroscopy
    • Flame Photometry
    • I.R. Spectroscopy
    • Mass Spectroscopy
    • NMR Spectroscopy
    • U.V./Visible Spectroscopy
  2. CHROMATOGRAPHIC METHODS:
    • Column Chromatography, Thin Layer Chromatography, Gas Liquid Chromatography, HPLC, LCMS, GCMS, Capillary Electrophoresis.