International Conference on Advances in Mechanical Engineering 2021 (ICAME-21) was held on 25th August 2021. The conference was conducted online due to the prevailing COVID situation. Dr. Mohammad Javed Hyder, Secretary ICAME-21 requested the chair of the inaugural session Dr. M. Mahabat Khan, Principal Advisor, Head of Mechanical Engineering Department to start the session. The motivational and encouraging inaugural speech was delivered by Dr. Mansoor Ahmed, Patron, Vice Chancellor of CUST. A total of 23 papers were presented along with five thought provoking keynote lectures by eminent international speakers, including Prof. Ruben Avila Rodriguez from Mexico, Prof. Mikhael Gorokhovski from France, Prof. Baris Yildiz from Turkey, Prof. Tariq Masood from UK, Prof. Metin Muradoglu from Turkey. The papers for presentation were selected after thorough and rigorous double blind peer review process by the competent panel of experts. It provided an excellent platform for the industrialist, engineers, scientist and technologists to exchange knowledge and benefit from the experiences of collogues. It is now an annual event and will be held regularly. The proceedings of the conference are available at the ICAME website: https://icame.cust.edu.pk/.