Dr. Mahira Zeeshan

Assistant Professor

mahira.zeeshan@cust.edu.pk

+92-51-111-555-666

PROFILE SUMMARY

Dr. Mahira Zeeshan has completed her Ph.D. degree in Pharmaceutics from “Quaid-i-Azam University, Islamabad, Pakistan”. She has been associated with academia and research for more than 5 years. Dr. Mahira published articles in reputable international journals (W category, Q1) with a cumulative research impact of >90. Her focus is on developing novel drug delivery strategies, exploring the world of nano pharmaceuticals with the preparation of several nanocarrier based drug targeting formulations, employing the latest techniques, introducing computational work in pharmaceutics, Quality by Design approach and design of experiments, in-dept formulation characterization using latest in vitro techniques, cell-based assays and development of in vivo animal models to determine the therapeutic efficacy of the nano formulations. Her thesis was declared best by foreign experts. Her academic life was remarkable with Gold Medals both in Pharm-D and MPhil Program for securing first position. She received academic scholarships including Riphah’s Musabiqat and Mumtaz merit, HEC-Indigenous and HEC-IRSIP fellowships (Germany) and also worked on the NRPU project. She is keen to proceed her research in pharmaceuticals development and drug delivery systems for various diseases. Her key achievements are development of novel drug delivery system for colon diseases.

QUALIFICATION
PhD	Pharmaceutics	Quaid-i-Azam University, Islamabad, Pakistan	2022
M.Phil	Pharmaceutics	Quaid-i-Azam University, Islamabad, Pakistan	2017
Pharm.D	Pharmaceutical Sciences	Riphah International University, Islamabad, Pakistan	2014

TEACHING EXPERIENCE
Assistant Professor	Faculty of pharmacy, Capital university of Science and Technology, Islamabad, Pakistan	Since -2023
Assistant Professor	National Excellence Institute, Islamabad	2023 – 2023

MEMBERSHIP OF PROFESSIONAL BODIES
PPC	Registered Pharmacist Punjab Pharmacy Council, Lahore

RESEARCH AREAS / INTERESTS
1.	Formulation Design & Development
2.	Pharmaceutical Nanotechnology
3.	Sustained Drug Delivery System
4.	Nano pharmaceutics

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SR.	JOURNAL PUBLICATIONS	YEAR
1	S. Altaf, M. Zeeshan, H. Ali, A. Zeb, I. Afzal, A. Imran, D. Mazhar, and S. Khan, “pH-sensitive tacrolimus loaded nanostructured lipid carriers for the treatment of inflammatory bowel disease,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 204, p. 114461, 2024.	2024
2	Q. U. Ain, M. Zeeshan, D. Mazhar, A. Zeb, I. Afzal, H. Ullah, H. Ali, A. Rahdar, and A. M. D´ıez-Pascual, “QbD-based fabrication of biomimetic hydroxyapatite embedded gelatin nanoparticles for localized drug delivery against deteriorated arthritic joint architecture,” Macromolecular Bioscience, vol. 24, no. 2, p. 2300336, 2024.	2024
3	G. Mustafa, D. Hassan, M. Zeeshan, G. Ruiz-Pulido, N. Ebrahimi, A. Mobashar, M. Pourmadadi, A. Rahdar, S. Sargazi, S. Fathi-karkan et al., “Advances in nanotechnology versus stem cell therapy for the theranostics of huntington’s disease,” Journal of Drug Delivery Science and Technology, vol. 87, p. 104774, 2023.	2023
4	S. Fathi-karkan, M. Zeeshan, M. Qindeel, R. E. Malekshah, A. Rahdar, and L. F. R. Ferreira, “NPs loaded with zoledronic acid as an advanced tool for cancer therapy,” Journal of Drug Delivery Science and Technology, vol. 87, p. 104805, 2023.	2023
5	M. Zeeshan, Q. U. Ain, B. Weigmann, D. Story, B. R. Smith, and H. Ali, “Dual pH and microbial-sensitive galactosylated polymeric nanocargoes for multi-level targeting to combat ulcerative colitis,” Asian Journal of Pharmaceutical Sciences, vol. 18, no. 4, p. 100831, 2023.	2023
6	D. Mazhar, N. U. Haq, M. Zeeshan, Q. U. Ain, H. Ali, S. Khan, and S. A. Khan, “Preparation, characterization, and pharmacokinetic assessment of metformin hcl loaded transfersomes co-equipped with permeation enhancer to improve drug bioavailability via transdermal route,” Journal of Drug Delivery Science and Technology, vol. 84, p. 104448, 2023.	2023
7	M. Zeeshan, Q. U. Ain, A. Sunny, F. Raza, M. Mohsin, S. Khan, B. Weigmann, and H. Ali, “Qbd-based fabrication of transferrin-anchored nanocarriers for targeted drug delivery to macrophages and colon cells for mucosal inflammation healing,” Biomaterials Science, vol. 11, no. 4, pp. 1373–1397, 2023.	2023
8	K. Lechner, M. Zeeshan, M. Noack, H. Ali, M. F. Neurath, and B. Weigmann, “Small but powerful: will nanoparticles be the future state-of-the-art therapy for ibd?” Expert Opinion on Drug Delivery, vol. 19, no. 3, pp. 235–245, 2022.	2022
9	E. Sana, M. Zeeshan, Q. U. Ain, A. U. Khan, I. Hussain, S. Khan, E. Lepeltier, and H. Ali, “Topical delivery of curcumin-loaded transfersomes gel ameliorated rheumatoid arthritis by inhibiting nf-κβ pathway,” Nanomedicine, vol. 16, no. 10, pp. 819–837, 2021.	2021
10	F. Sabir, M. Zeeshan, U. Laraib, M. Barani, A. Rahdar, M. Cucchiarini, and S. Pandey, “Dna based and stimuli-responsive smart nanocarrier for diagnosis and treatment of cancer: Applications and challenges,” Cancers, vol. 13, no. 14, p. 3396, 2021.	2021
11	M. Barani, M. Zeeshan, D. Kalantar-Neyestanaki, M. A. Farooq, A. Rahdar, N. K. Jha, S. Sargazi, P. K. Gupta, and V. K. Thakur, “Nanomaterials in the management of gram-negative bacterial infections,” Nanomaterials, vol. 11, no. 10, p. 2535, 2021.	2021
12	F. Sabir, M. Qindeel, M. Zeeshan, Q. Ul Ain, A. Rahdar, M. Barani, E. Gonz´alez, and M. A. Aboudzadeh, “Onco-receptors targeting in lung cancer via application of surface-modified and hybrid nanoparticles: A cross-disciplinary review,” Processes, vol. 9, no. 4, p. 621, 2021.	2021
13	M. Zeeshan, A. Atiq, Q. U. Ain, J. Ali, S. Khan, and H. Ali, “Evaluating the mucoprotective effects of glycyrrhizic acid-loaded polymeric nanoparticles in a murine model of 5-fluorouracil-induced intestinal mucositis via suppression of inflammatory mediators and oxidative stress,” Inflammopharmacology, vol. 29, pp. 1539–1553, 2021.	2021
14	M. Zeeshan, H. Ali, Q. U. Ain, M. Mukhtar, R. Gul, A. Sarwar, and S. Khan, “A holistic qbd approach to design galactose conjugated plga polymer and nanoparticles to catch macrophages during intestinal inflammation,” Materials Science and Engineering: C, vol. 126, p. 112183, 2021.	2021
15	M. Barani, M. Reza Hajinezhad, S. Sargazi, M. Zeeshan, A. Rahdar, S. Pandey, M. Khatami, and F. Zargari, “Simulation, in vitro, and in vivo cytotoxicity assessments of methotrexate-loaded ph-responsive nanocarriers,” Polymers, vol. 13, no. 18, p. 3153, 2021.	2021
16	M. Mukhtar, E. F´enyes, C. Bartos, M. Zeeshan, and R. Ambrus, “Chitosan biopolymer, its derivatives and potential applications in nano-therapeutics: A comprehensive review,” European Polymer Journal, vol. 160, p. 110767, 2021.	2021
17	M. Mukhtar, M. Zesshan, S. Khan, G. Shahnaz, S. A. Khan, H. S. Sarwar, R. A. Pasha, and H. Ali, “Fabrication and optimization of ph-sensitive mannose-anchored nano-vehicle as a promising approach for macrophage uptake,” Applied Nanoscience, vol. 10, pp. 4013–4027, 2020	2020
18	M. Mukhtar, E. Pallagi, I. Cs´oka, E. Benke, ´A. Farkas, M. Zeeshan, K. Buri´an, D. K´okai, and R. Ambrus, “Aerodynamic properties and in silico deposition of isoniazid loaded chitosan/thiolated chitosan and hyaluronic acid hybrid nanoplex dpis as a potential tb treatment,” International Journal of Biological Macromolecules, vol. 165, pp. 3007–3019, 2020.	2020
19	M. Zeeshan, H. Ali, S. Khan, S. A. Khan, and B. Weigmann, “Advances in orally-delivered ph-sensitive nanocarrier systems; an optimistic approach for the treatment of inflammatory bowel disease,” International journal of pharmaceutics, vol. 558, pp. 201–214, 2019.	2019
20	M. Zeeshan, H. Ali, S. Khan, M. Mukhtar, M. I. Khan, and M. Arshad, “Glycyrrhizic acid-loaded ph-sensitive poly-(lactic-co-glycolic acid) nanoparticles for the amelioration of inflammatory bowel disease,” Nanomedicine, vol. 14, no. 15, pp. 1945–1969, 2019.	2019
21	Q. Ain, M. Zeeshan, S. Khan, and H. Ali, “Biomimetic hydroxyapatite as potential polymeric nanocarrier for the treatment of rheumatoid arthritis,” Journal of Biomedical Materials Research Part A, vol. 107, no. 12, pp. 2595–2600, 2019.	2019

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