Dr-Erum

Dr. Erum Dilshad

Associate Professor
PROFILE SUMMARY

Her research is focused on Nanobiotechnology, producing metallic nanoparticles by chemical and biological methods involving a green chemistry approach. She evaluates these metallic nanoparticles for their anticancer properties against cancer cell lines, including breast and liver cancer. Research also involves producing both medicinal and edible crops transgenics to enhance secondary metabolites and tolerance against biotic and abiotic stress along with their phytochemical analysis. Furthermore, her research is focused on computer-aided drug designing and screening biomolecules for their activities and effectiveness against various ailments, including cancer. She has been enlisted in AD World Scientist Ranking and as a Productive Scientist of Pakistan in 2016 and 2017, under age 40 by the Pakistan Council for Science and Technology Pakistan (PCST). To date, she has a significant number of ISI-indexed publications, and the total impact factor is 100. She has authored 10 book chapters with internationally recognized publishers and a complete book with Bentham Publishers.

QUALIFICATION
Ph.D Biochemistry/Plant Biotechnology Quaid-i-Azam University Islamabad 2016
M.phil Biochemistry/Molecular Biology Quaid-i-Azam University Islamabad 2010
M.Sc Biochemistry Quaid-i-Azam University Islamabad 2008
TEACHING EXPERIENCE
Associate Professor Capital University of Science and Technology (CUST), Islamabad Since – 2023
Assistant Professor Capital University of Science and Technology (CUST), Islamabad 2016 – 2022
INDUSTRIAL EXPERIENCE
Research Associate Quaid-i-Azam University Islamabad 2015 – 2016
Visiting Researcher University of Barcelona, Spain 2015 – 2015
Laboratory Scientist Shifa International Hospital Islamabad 2010 – 2014
MANAGEMENT EXPERIENCE
Patron GENIX Since – 2018
RESEARCH AREAS / INTERESTS
1. Cloning
2. Plant Biotechnology
3. Phytochemistry
4. DNA Barcoding
RESEARCH SUPERVISION
1. MS Determination of Active Constituents of Artemisia annua Against Viral Main Protease Mpro/CLpro to Treat SARS-CoV-2
2. MS Immunoregulatory and anti-inflammatory effects of bioactive compounds of garlic against Covid-19.
3. MS Identification of Active Constituents of Artemisia carvifolia against Breast Cancer
4. MS Identification of Anti-Viral Metabolites of Nigella sativa
5. MS Determination of potential inhibitors of SARS-COVID-19 present in Senna alexandrina
6. MS Determination of Potential Antioxidants of Artemisia annua by Computational Approaches
7. MS Identification of Anti-inflammatory Metabolites from Trigonella Foenum Graecum
8. MS Design, development and evaluation of antiseptic wound healing herbal pad
9. MS Prevalence of Hepatitis B and C in General Population and Transgender Population of Rawalpindi.
10. MS Pharmacological evaluation of Zinc oxide nanoparticles synthesized by using leaf extract of Bryophyllum pinnatum.
11. MS Synthesis and Evaluation of ZnO Nanoparticles of Trigonella foenum for their Biological Activities
12. MS Chromium Reduction and Plant Growth Promotion by Staphylococcus arlettae in Wheat
13. MS Greensynthesis,Characterizationand Therapeuticevaluation of zincoxide Nanoparticles using extractof Nigellasativa
14. MS Therapeutic evaluation of silver nanoparticles synthesized using Bryophyllum pinnatum plant extract
15. MS Biological Evaluation of Seeds of Trigonella Foenum (Methi) Plant and their Siver Nanoparticles
16. MS Biological evaluation of Silver Nanoparticles of Mentha Asiatica
17. MS Chemical Synthesis of Diversified Silver Nanoparticles along with Characterization and Biological Evaluation
18. MS Risk Factors Associated with Alteration of Hematological and Biochemical Parameters in G6PD Deficiency
19. MS Green Synthesis and Characterization of Silver Nanoparticles Using Leaf Extract of Artemisia Carvifolia and their Anti-Bacterial, Anti-Fungal, Anti-Oxidant, Cytotoxic Activities.
20. MS Optimization of Conditions for Micropropogation of Spinach (Spinacia oleracea).

SR.JOURNAL PUBLICATIONSYEAR
1Erum Dilshad, Farkhanda Mehmood, Rida Tariq, Anum Munir, Sahar Fazal (2022). Chemical Constituents of Artemisia annua are Potent Inhibitors of Alpha-Amylase in Diabetes II. Life and Science. 3(1). 1-102022
2Iqra Bashir, Mubarak Ali Khan, Erum Dilshad, Bara Siyo, Ejaz Hussain & Iftikhar Ali (2021) Antioxidant and anticancer silver nanoparticles of Mentha asiatica aerial part extract: a novel study, Inorganic and Nano-Metal Chemistry, DOI: 10.1080/24701556.2021.20219452021
3Sadia Safi, Yasmin Badshah, Maria Shabbir, Kainat Zahra, Erum Dilshad, Dara Al-disi, Dara Assad Aldisi, Mahmoud M. Abulmeaty, and Suhail Razak. “Predicting 3D structure, cross-talks and prognostic significance of KLF 9 in cervical cancer.” Frontiers in Oncology: 5382
4Hammad Ismail, Muhammad Umar Ijaz, Muhammad Zeeshan Bhatti, Hajira Liaquat, Neelam Nawaz, Iqra Zafar, Mohamed A. Nassan, Rania M. Waheed, Reem H. Badr, Sara Latif, Muhammad Suleman Malik, Erum Dilshad, Mohammad Tahir Waheed, Gaber El-Saber Batiha (2021). Effect of Phoenix dactylifera extracts on anti-inflammatory, anticoagulant, analgesic and antidepressant activities. Wulfenia. 28(2)2021
5Zahoor ul Haq Ijaz Ali, Ghazala Hafeez Rizwani, Urooj Zafar, Atif Ali Khan Khalil, Zahid Farooq, Erum Dilshad, Abdul Baseer, Zahid Khan, and Muhammad Romman, Saqibullah (2021). Antimicrobial activities of Dalbergia sissoo DC. and Caralluma tuberculate. Bioscience Research. 18(2). 1802-18092021
6Erum Dilshad, Zainab Nooruddin, Shadab Shaukat, Anum Munir, Syeda Marriam Bakhtiar and Hammad Ismail (2021). Identification of Stress-induced miRNA and their targets in Solanum lycopersicum. Current Chinese Science. DOI: 10.2174/22102981016662106170956272021
7Syeda Marriam Bakhtiar, Syeda Eeman Zahra Bokhari, Iqra Riasat and Erum Dilshad (2021). Elucidating the Genetic Factors Contributing Towards Susceptibility and Severity of Covid 19. Current Chinese Science. DOI: 10.2174/22102981016662109140856272021
8Khayam, Asma Umer, Harsh Patel, Nicholas A. Faiola, Andre E. Figueroa Milla, Erum Dilshad, Bushra Mirza, Ying Huang, and M. Saeed Sheikh. “Quinovic acid purified from medicinal plant Fagonia indica mediates anticancer effects via death receptor 5.” Molecular and Cellular Biochemistry (2020): 1-112020
9Kiani, Bushra Hafeez, Waqas Khan Kayani, Asma Umer Khayam, Erum Dilshad, Hammad Ismail, and Bushra Mirza. “Artemisinin and its derivatives: a promising cancer therapy.” Molecular Biology Reports (2020): 1-162020
10Latif, Sara, Hammad Ismail, Muhammad Rashid Khan, Amna Abdul Rahim, Ramsha Mehboob, Erum Dilshad, Moniba Sajid, Syed Ihtisham Haider, Sadaf Anwaar, and Muhammad Naveed Majeed. “Pharmacological evaluation of Acacia modesta bark for antipyretic, anti-inflammatory, analgesic, antidepressant and anticoagulant activities in Sprague Dawley rats.” Pakistan Journal of Pharmaceutical Sciences 33, no. 3 (2020)2020
11Erum Dilshad, Hammad Ismail, Mubarak Ali Khan, Rosa Maria Cusido, and Bushra Mirza. “Metabolite profiling of Artemisia carvifolia Buch transgenic plants and estimation of their anticancer and antidiabetic potential.” Biocatalysis and Agricultural Biotechnology 24 (2020): 1015392020
12Mehfooz, Haroon, Aamer Saeed, Muhammad Faisal, Fayaz Ali Larik, Urooj Muqadar, Saira Khatoon, Pervaiz Ali Channar et al. “Facile one-pot synthesis, butyrylcholinesterase and α-glucosidase inhibitory activities, structure–activity relationship, molecular docking and DNA–drug binding analysis of Meldrum’s acid derivatives.” Research on Chemical Intermediates (2020): 1-202020
13Iqra Younus, Hammad Ismail, Chahat Batool Rizvi, Erum Dilshad, Kiran Saba, Bushra Mirza, Mohammad Tahir Waheed. J Pharm Pharmacogn 7 (5) (2019): 343-3552019
14Erum Dilshad, Syeda Sojla Tazeem, Zainab Bashir, Ammar Hamza Iqbal, Adeel Saddique Khokhar, Naqoosh Zahra, Mubarak Ali Khan, Hammad Ismail, Maria Shabbir. “Silver nanoparticles of Aloe vera gel as strong therapeutic candidates.” Int. J. Biosci (2019). 15(1), 360-3732019
15Kazmi, Abeer, Mubarak Ali Khan, Huma Ali, Erum Dilshad. “Biotechnological approaches for production of bioactive secondary metabolites in Nigella sativa: an up-to-date review.” International Journal of Secondary Metabolite 6, no. 2 (2019): 172-1952019
16Ali, Huma, Mubarak Ali Khan, Waqas Khan Kayani, Erum Dilshad, Rehana Rani, and Raham Sher Khan. “Production of biomass and medicinal metabolites through adventitious roots in Ajuga bracteosa under different spectral lights.” Journal of Photochemistry and Photobiology B: Biology 193 (2019): 109-1172019
17Zafar, Sara, Erum Dilshad, Hammad Ismail, Chahat Batool Rizvi, and Bushra Mirza. “Rol genes enhance content of artemisinin and other secondary metabolites in Shennong hybrid of Artemisia annua.” Chinese Herbal Medicines (2019)2019
18Rehman, Samiya, Ken Keefover-Ring, Ihsan ul Haq, Erum Dilshad, Mohammad Imran Khan, Nosheen Akhtar, and Bushra Mirza. “Drier Climatic Conditions Increase Withanolide Content of Withania coagulans Enhancing Its Inhibitory Potential Against Human Prostate Cancer Cells.” Applied biochemistry and biotechnology (2018): 1-212018
19Munir, Anum, Shahid Hussain, and Erum Dilshad. “Silver nanoparticles conjugated with Neurotrophin 3 upregulate myelin gene transcription pathway.” Journal of theoretical biology 459 (2018): 111-1182018
20Larik, Fayaz Ali, Aamer Saeed, Muahmmad Faisal, Pervaiz Ali Channar, Syed Sikandar Azam, Hammad Ismail, Erum Dilshad, and Bushra Mirza. “Synthesis, molecular docking and comparative efficacy of various alkyl/aryl thioureas as antibacterial, antifungal and α-amylase inhibitors.” Computational biology and chemistry 77 (2018): 193-1982018
21Waqas khan kiani, Bushra Hafeez Kiani, Erum Dilshad, Bushra Mirza, “Biotechnological approaches for artemisinin production in Artemisia”, World Journal of Microbiology and Biotechnology, No: 42018
22Hammad Ismail, Ammara Rasheed, Ihsan ul Haq, Laila Jafri, Nazif Ullah, Erum Dilshad, Moniba Sajid, Bushra Mirza, “Five indigenous plants of Pakistan with anti-nociceptive, antiinflammatory, anti-depressant and anti-coagulant properties in Sprague Dawley rats”, Evidence based complementary and alternative medicine2017
23Aamer Saeed, Pervaiz Ali Channar, Fayaz Ali Larik, Farukh Jabeen, Urooj Muqadar, Shomaila Saeed, Ulrich Flörke, Hammad Ismail, Erum Dilshad, Bushra Mirza , “Design, Synthesis, Molecular docking studies of organotin-drug derivatives as multi-target agents against antibacterial, antifungal, a-amylase, a-glucosidase and buytyrlcholinesterase”, Inorganica Chimica Acta, Pages: 204-2132017
24Ismail, Hammad, Erum Dilshad, Mohammad Tahir Waheed, and Bushra Mirza, “Transformation of Lettuce with rol ABC Genes: Extracts Show Enhanced Antioxidant, Analgesic, Anti-Inflammatory, Antidepressant, and Anticoagulant Activities in Rats”, Applied Biochemistry and Biotechnology (Springer), Pages: 1-202017
25Fayaz Ali Larik, Aamer Saeed, Pervaiz Ali Channar, Hammad Ismail, Erum Dilshad, Bushra Mirza, “New 1-octanoyl-3-aryl thiourea derivatives: Solvent-free synthesis, characterization and multi-target biological activities”, Bangladesh Journal of Pharmacology, Pages: 894-9022017
26Kayani, Waqas Khan, Erum Dilshad, Tanveer Ahmed, Hammad Ismail, and Bushra Mirza, “Evaluation of Ajuga bracteosa for antioxidant, anti-inflammatory, analgesic, antidepressant and anticoagulant activities”, BMC Complementary and Alternative Medicine (Springer), No: 1, Pages: 3752016
27Ismail, Hammad, Erum Dilshad, Mohammad Tahir Waheed, Moniba Sajid, Waqas Khan Kayani, and Bushra Mirza, “Transformation of Lactuca sativa L. with rol C gene results in increased antioxidant potential and enhanced analgesic, anti-inflammatory and antidepressant activities in vivo”, 3 Biotech (Springer), No: 2, Pages: 2152016
28Erum Dilshad, Sara zafar, Hammad Ismail, Mohammad Tahir Waheed, Rosa Maria Cusido, Javier Palazon, Bushra Mirza, “Effect of Rol Genes on Polyphenols Biosynthesis in Artemisia annua and Their Effect on Antioxidant and Cytotoxic Potential of the Plant”, Appl Biochem Biotechnol, No: 8, Pages: 1456-14582016
29Erum Dilshad, Hammad Ismail, Ihsan-ul-Haq, Rosa Maria Cusido, Javier Palazon, Karla Ramirez Estrada, Bushra Mirza, “Rol genes enhance the biosynthesis of antioxidants in A. carvifolia Buch”, BMC Plant Biology2016
30Erum Dilshad, Rosa Maria Cusido, Javier Palazon, Karla Ramirez Estrada, Mercedes Bonfill, Bushra Mirza, “Enhanced artemisinin yield by expression of rol genes in Artemisia annua”, Malaria Journal, Pages: 4242015
31Erum Dilshad, Rosa Maria Cusido, Karla Ramirez Estrada, Mercedes Bonfill, Bushra Mirza , “Genetic Transformation of Artemisia carvifolia Buch with rol Genes Enhances Artemisinin Accumulation”, Plos One, No: 10, Pages: e01402662015
32Erum Dilshad, Bushra Mirza1, Muhammad Shabbir, Zia-ul- Haq, Zareen Akhter, “Biological Evaluation of Aza-Heterocyclic Derivatives and their Intermediates”, World J Pharmaceutical Sciences, No: 6, Pages: 2111-21262014
33Ghulam Murtaza, Muhammad Khawar Rauf, Amin Badshah, Masahiro Ebihara, Muhammad Said, Marcel Gielen, Dick de Vos, Erum Dilshad, Bushra Mirza , “Synthesis, structural characterization and in vitro biological screening of some homoleptic copper(II) complexes with substituted guanidines”, European J Chemistry, Pages: 26-352012

SR.CONFERENCE PUBLICATIONSYEAR
1Amna Naheed Khan, Erum Dilshad, Bushra Mirza (2020). “Agrobacterium tumefaciens Mediated Genetic Transformation of Lycopersicon esculentum Mill. For Enhancement of Abiotic Stress Tolerance. C-BICS 2020 CUST Islamabad.2020
2Syeda Sojla, Zainab Bashir, Erum Dilshad. “Green Synthesis and Characterization of Silver Nanoparticles Using Alo vera Plant Gel and Their Biological Evaluation”.1st National Conference on Medicinal Plant Research. Karakoram International University Gilgit Baltistan. 29-31 Aug 2018.2018
3ISESCO WINS 2016 conference Quaid-i-Azam University Islamabad March 2016. Genetic transformation of Artemisia carvifolia Buch with rol genes for enhancement of secondary metabolites. Poster Presentation.2016
44th International Conference on Biological and Computer Science. December 14, 2016. Genetic transformation of Lycopersicon esculentum Mill. using an abiotic stress tolerance gene. Poster presentation2016

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