yasir

Mr. Muhammad Yasir (MS CUI, Islamabad)

Lecturer
PROFILE SUMMARY

Mr. Muhammad Yasir a Lecturer in Pharmacy passionate about teaching and research holding two years of experience in medical devices and two & half years in academia with skill-based research approaches in Antimicrobial Resistance, Computer-Aided Drug Designing, Pharmacogenomics, and Microbiology & Immunology. Deep insights in identifying research gaps, innovative ideas hunting, shifts and positioning students for the future.

QUALIFICATION
MS Microbiology & Immunology COMSATS University, Islamabad, Pakistan 2016
Pharm.D Pharmaceutical Sciences University of Peshawar, Peshawar, Pakistan 2013
TEACHING EXPERIENCE
Lecturer Capital University of Science and Technology (CUST), Islamabad Since – 2019
PROFESSIONAL EXPERIENCE
Qualified Personnel Medical Devices (MEDCOMP & BARD), Rawalpindi. Jan 2015 – Feb 2017
MEMBERSHIP OF PROFESSIONAL BODIES
Member Pharmacy Council, Pakistan
HONORS & AWARDS
1. Top twenty position holder in F. Sc.
2. 12th National One week training course on “Modern techniques in Biotechnology” NIBGE, Faisalabad, Pakistan 2014.
3. One day workshop on young researcher’s skill development, Agriculture University, Peshawar, Pakistan 2012.
4. One week training course on ‘Medicinal Plants & Herbal Medicine’ PCSIR Laboratories Peshawar, Pakistan 2009.
RESEARCH AREAS / INTERESTS
  1. Drug designing;
  2. Computer Aided Drug Designing (CADD);
  3. Antimicrobial Resistance;
  4. Pharmacogenomics;
  5. Microbiology & Immunology
RESEARCH EXPERIENCE
1. “Isolation and Characterization of Vibrio cholerae in clinical samples from Pakistan” (This project executed successfully which is designed with the aim to isolate and characterize the V. cholerae in clinical samples from different geographical locations in Pakistan. And it’s concluded with better insight in to their biochemical, virulent and antibiotic resistance properties with the special emphasis on ESBL (Extended Spectrum β Lactamases) and NDM-1(New Delhi Metallo β Lactamases) screening aspects. Which will allow the containment of the disease at the epicenter by prescription of appropriate antibiotics).
2. Project title: “Type Six Secretion System (T6SS) and Dam Methylation Patterns in Vibrio cholerae” (This project is completed with the aim to understand the T6SS genes and distribution of dam methylation patterns in Vibrio cholerae genomes belonged to two Pakistan Subclades 1 & 2 (PSC-1 and PSC-2). These whole genome sequencing of Vibrio cholerae was performed on clinical isolates collected in Pakistan during the cholera outbreak of 2010 and 2011 floods).
3. Project Title: “Metagenome analysis of pyrosequencing data from uranium contaminated soil using GENEIOUS software” (During my MS studies, I completed this research project using the Next Generation Sequence Analysis technique employing the GENEIOUS software for metagenomics data analysis which was obtained from the uranium contaminated soil; and concluded with the significant results).
4. Project Title: “Isolation and Characterization of Vibrio cholerae Specific Phages from Environmental and Clinical Sources” (I also teamed to work in lab on this project which was aimed to collect clinical and environmental samples and characterize choleraphages and determine host range of these phages. In which we employed a comprehensive methodological approaches of Isolation of lytic phages from clinical samples and preparation of genomic DNA and phage isolation by phage plaque assay on variety of V. cholerae host strains).
5. Mycobacterium tuberculosis drug designing project title: “Identification of novel inhibitors of M. tuberculosis by targeting FadD32 protein” (This project is designed with the aim to provide a solid framework for future understanding of biology in perspective of this target (FadD32) of Mycobacterium tuberculosis. It will result in therapeutic intervention with a new gateway to novel treatment strategies. The project will provide the opportunity for man power development and research activities regarding TB drug discovery and designing).
6. PharmD Thesis Project Title: “Dose adjustment in patients with renal impairment” (The purpose of this report was to present significant findings of medication histories, pharmacotherapy (especially antibiotics) provided in the hospital to patients with renal impairment (Chronic kidney disease), drugs prescribing pattern, outcome of therapy, drug- drug interactions, adverse effects of drugs reporting; and to report drug information or patient counseling related activities).
7. Infectious Diseases Rotation (This infectious diseases rotation during my undergrad from April 2011-June 2011 was aimed to understand all aspects of infectious diseases and use of anti-infective agents. Which aided my in depth understanding of clinical microbiology, the use, and spectrum of activity of antibiotics, pharmacokinetic and pharmacodynamics properties and adverse effects of antibiotics).
JOURNAL PUBLICATIONS
1. S. Zeb, M. A. Shah, M. Yasir, H. M. Awan, P. Prommeenate, A. Klanchui, Br. W. Wren, N. R. Thomson, H. Bokhari, “Type III secretion system confers enhanced virulence in clinical non-O1/nonO139 Vibrio cholera” Microbial Pathogenesis, Vol. 135, no. 103645, 2019
CONFERENCE PUBLICATIONS
1. 1. Yasir M, Syed Q, Perveen N, Khan K, Gondal A, Sattar S, Sha M A, Wren W B, Thomsan N, Bokhari H. “Vibrio cholerae: Problem & Solution”, in proceedings of 2016 IBCAST International Conference on Applied Sciences & Technology, 2016.
2. 2. Yasir M, Syed Q, Naureen N, Fatmi Q, N, Nadeem M, Nasir A, Bokhari H. “Type VI secretion system and Dam methylation pattern in Vibrio cholerae”, in proceedings of 2015 Training Workshop, Department of Computer Sciences, University of Cambridge, 2015.
POSTER PRESENTATION
1. Yasir M, Syed Q, Perveen N, Khan K, Gondal A, Sattar S, Sha M A, Bokhari H. “Multiple antibiotic resistant Vibrio cholerae O1, non-O1/non-O139 isolates from environmental and clinical sources in Pakistan”. 6th Annual public health scientific conference, Health Services Academy, Islamabad, Pakistan. 11-12 Dec 2015.
2. Yasir M, Syed Q, Naureen N, Fatmi Q, N, Nadeem M, Nasir A, Bokhari H. “Type VI secretion system and Dam methylation pattern in Vibrio cholerae”. Training Workshop, Department of Computer Sciences, University of Cambridge, UK, 23-27 March 2015 (Organized by EUH2020 Funding and COST Action BM1102).
3. Yasir M, Syed Q, Perveen N, Khan K, Gondal A, Sattar S, Sha M A, Wren W B, Thomsan N, Bokhari H. “Vibrio cholerae: Problem & Solution”. IBCAST 13th International Bhurban Conference on Applied Sciences & Technology, NCP, Islamabad, Pakistan 12-16 Jan 2016.
4. Yasir M, Habib Bokhari. “Detection of ESBL Producing and NDM-1 Carrying Vibrio cholerae Isolated from Pakistan” 7th International Conference on Biological & Computational Sciences (C-BICS 2019), November 28,2019.

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